Cargando…

Inflammation-Induced Mucosal KYNU Expression Identifies Human Ileal Crohn’s Disease

The widely varying therapeutic response of patients with inflammatory bowel disease (IBD) continues to raise questions regarding the unclarified heterogeneity of pathological mechanisms promoting disease progression. While biomarkers for the differentiation of Crohn’s disease (CD) versus ulcerative...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huhn, Meik, Herrero San Juan, Martina, Melcher, Balint, Dreis, Caroline, Schmidt, Katrin G., Schwiebs, Anja, Collins, Janet, Pfeilschifter, Josef M., Vieth, Michael, Stein, Jürgen, Radeke, Heinfried H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290775/ https://www.ncbi.nlm.nih.gov/pubmed/32384670 http://dx.doi.org/10.3390/jcm9051360

Ejemplares similares

Enhanced CXCR4 Expression of Human CD8(Low) T Lymphocytes Is Driven by S1P(4)
por: Burkard, Tobias, et al.
Publicado: (2021)

Tissue Cytokine IL-33 Modulates the Cytotoxic CD8 T Lymphocyte Activity During Nutrient Deprivation by Regulation of Lineage-Specific Differentiation Programs
por: Dreis, Caroline, et al.
Publicado: (2019)

Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells
por: Schwiebs, Anja, et al.
Publicado: (2017)

Activation-Induced Cell Death of Dendritic Cells Is Dependent on Sphingosine Kinase 1
por: Schwiebs, Anja, et al.
Publicado: (2016)

S1P Lyase Regulates Intestinal Stem Cell Quiescence via Ki-67 and FOXO3
por: Schwiebs, Anja, et al.
Publicado: (2021)

Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study
por: Schmidt, Katrin G., et al.
Publicado: (2017)

Interferon-Beta Increases Plasma Ceramides of Specific Chain Length in Multiple Sclerosis Patients, Unlike Fingolimod or Natalizumab
por: Ottenlinger, Florian M., et al.
Publicado: (2016)

Differential expression of CD8 defines phenotypically distinct cytotoxic T cells in cancer and multiple sclerosis
por: Burkard, Tobias, et al.
Publicado: (2022)

Betulin - a plant-derived cytostatic drug - enhances antitumor immune response
por: Pfarr, Kathrin, et al.
Publicado: (2014)

Discovering KYNU as a feature gene in hidradenitis suppurativa
por: Liang, Chen, et al.
Publicado: (2023)

Defective IL-23/IL-17 Axis Protects p47phox−/− Mice from Colon Cancer
por: Richter, Cornelia, et al.
Publicado: (2017)

Simultaneous and Dose Dependent Melanoma Cytotoxic and Immune Stimulatory Activity of Betulin
por: Pfarr, Kathrin, et al.
Publicado: (2015)

KYNU-related transcriptome profile and clinical outcome from 2994 breast tumors
por: Li, Yiliang, et al.
Publicado: (2023)

Antimicrobial activity, in vitro anticancer effect (MCF-7 breast cancer cell line), antiangiogenic and immunomodulatory potentials of Populus nigra L. buds extract
por: Kis, Brigitta, et al.
Publicado: (2022)

An Ileal Crohn's Disease Gene Signature Based on Whole Human Genome Expression Profiles of Disease Unaffected Ileal Mucosal Biopsies
por: Zhang, Tianyi, et al.
Publicado: (2012)

Botanical Therapeutics: Phytochemical Screening and Biological Assessment of Chamomile, Parsley and Celery Extracts against A375 Human Melanoma and Dendritic Cells
por: Danciu, Corina, et al.
Publicado: (2018)

KYNU, a novel potential target that underpins CD44‐promoted breast tumour cell invasion
por: Al‐Mansoob, Maryam, et al.
Publicado: (2021)

KYNU as a Biomarker of Tumor-Associated Macrophages and Correlates with Immunosuppressive Microenvironment and Poor Prognosis in Gastric Cancer
por: Shen, Kaiyu, et al.
Publicado: (2023)

Replacing Endoscopy with Magnetic Resonance Enterography for Mucosal Activity Assessment in Terminal Ileal Crohn’s Disease: Are We There Yet?
por: Bohra, Anuj, et al.
Publicado: (2023)

A Comprehensive Assessment of Apigenin as an Antiproliferative, Proapoptotic, Antiangiogenic and Immunomodulatory Phytocompound
por: Ghițu, Alexandra, et al.
Publicado: (2019)

Differential Gene Expression and Methylation Analysis of Melanoma in TCGA Database to Further Study the Expression Pattern of KYNU in Melanoma
por: Wang, Min, et al.
Publicado: (2022)

A Food Impaction in Crohn’s Ileal Stricture
por: Hokama, Akira, et al.
Publicado: (2010)

Sphingosine 1-Phosphate Modulates Antigen Capture by Murine Langerhans Cells via the S1P(2) Receptor Subtype
por: Japtok, Lukasz, et al.
Publicado: (2012)

Ileal Crohn's disease fistulating into a Meckel's diverticulum
por: Zammit, Andrew Philip, et al.
Publicado: (2022)

Ileal and colonic Crohn's disease: Does location makes a difference in therapy efficacy?
por: Atreya, Raja, et al.
Publicado: (2022)

Ileal Signet Ring Cell Carcinoma Masked by Crohn Disease
por: Hammami, Muhammad Baraa, et al.
Publicado: (2020)

An Update Review on the Paneth Cell as Key to Ileal Crohn's Disease
por: Wehkamp, Jan, et al.
Publicado: (2020)

Relating the transcriptome and microbiome by paired terminal ileal Crohn disease
por: Cai, Chenwen, et al.
Publicado: (2021)

Targeting Mitochondrial Damage as a Therapeutic for Ileal Crohn’s Disease
por: Alula, Kibrom M., et al.
Publicado: (2021)

Identification and Characterisation of Pseudomonas 16S Ribosomal DNA from Ileal Biopsies of Children with Crohn's Disease
por: Wagner, Josef, et al.
Publicado: (2008)

Ileal microcirculation and mucosal acidosis during hyperdynamic porcine endotoxemia
por: Tugtekin, I, et al.
Publicado: (2000)

Alterations of the Ileal and Colonic Mucosal Microbiota in Canine Chronic Enteropathies
por: Cassmann, Eric, et al.
Publicado: (2016)

Nod2: A Critical Regulator of Ileal Microbiota and Crohn’s Disease
por: Sidiq, Tabasum, et al.
Publicado: (2016)

Ileal Crohn's Disease Exhibits Similar Transmural Fibrosis Irrespective of Phenotype
por: Tavares de Sousa, Helena, et al.
Publicado: (2021)

Case report of metastatic breast cancer mimicking ileal Crohn's disease
por: Maharajh, Sandeep, et al.
Publicado: (2021)

The ileal fungal microbiota is altered in Crohn's disease and is associated with the disease course
por: Olaisen, Maya, et al.
Publicado: (2022)

Orbital Myositis in a Patient With Ileal Crohn's Disease in Remission on Vedolizumab
por: Sandhu, Sunny, et al.
Publicado: (2022)

Folic Acid and Vitamin B12 Prevent Deleterious Effects of Rotenone on Object Novelty Recognition Memory and Kynu Expression in an Animal Model of Parkinson’s Disease
por: Kretzschmar, Gabriela Canalli, et al.
Publicado: (2022)

Quality of Life Is Related to Fecal Calprotectin Concentrations in Colonic Crohn Disease and Ulcerative Colitis, but not in Ileal Crohn Disease
por: Gauss, Annika, et al.
Publicado: (2016)

Ileal mucosal bile acid absorption is increased in Cftr knockout mice
por: Stelzner, Matthias, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_efv8aq4lb857cuo5gthfl0nl6u