LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction

The cholesterol-sensing nuclear receptor liver X receptor (LXR) and the glucose-sensing transcription factor carbohydrate responsive element-binding protein (ChREBP) are central players in regulating glucose and lipid metabolism in the liver. More knowledge of their mechanistic interplay is needed t...

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Detalles Bibliográficos
Autores principales: Fan, Qiong, Nørgaard, Rikke Christine, Grytten, Ivar, Ness, Cecilie Maria, Lucas, Christin, Vekterud, Kristin, Soedling, Helen, Matthews, Jason, Lemma, Roza Berhanu, Gabrielsen, Odd Stokke, Bindesbøll, Christian, Ulven, Stine Marie, Nebb, Hilde Irene, Grønning-Wang, Line Mariann, Sæther, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290792/
https://www.ncbi.nlm.nih.gov/pubmed/32414201
http://dx.doi.org/10.3390/cells9051214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290792/
https://www.ncbi.nlm.nih.gov/pubmed/32414201
http://dx.doi.org/10.3390/cells9051214

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