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LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction
The cholesterol-sensing nuclear receptor liver X receptor (LXR) and the glucose-sensing transcription factor carbohydrate responsive element-binding protein (ChREBP) are central players in regulating glucose and lipid metabolism in the liver. More knowledge of their mechanistic interplay is needed t...
Autores principales: | Fan, Qiong, Nørgaard, Rikke Christine, Grytten, Ivar, Ness, Cecilie Maria, Lucas, Christin, Vekterud, Kristin, Soedling, Helen, Matthews, Jason, Lemma, Roza Berhanu, Gabrielsen, Odd Stokke, Bindesbøll, Christian, Ulven, Stine Marie, Nebb, Hilde Irene, Grønning-Wang, Line Mariann, Sæther, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290792/ https://www.ncbi.nlm.nih.gov/pubmed/32414201 http://dx.doi.org/10.3390/cells9051214 |
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