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A Multiparametric Assay Platform for Simultaneous In Vivo Assessment of Pronephric Morphology, Renal Function and Heart Rate in Larval Zebrafish

Automated high-throughput workflows allow for chemical toxicity testing and drug discovery in zebrafish disease models. Due to its conserved structural and functional properties, the zebrafish pronephros offers a unique model to study renal development and disease at larger scale. Ideally, scoring o...

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Detalles Bibliográficos
Autores principales: Steenbergen, Petrus J., Heigwer, Jana, Pandey, Gunjan, Tönshoff, Burkhard, Gehrig, Jochen, Westhoff, Jens H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290829/
https://www.ncbi.nlm.nih.gov/pubmed/32443839
http://dx.doi.org/10.3390/cells9051269