Initial Steps for the Development of a Phage-Mediated Gene Replacement Therapy Using CRISPR-Cas9 Technology

p53 gene (TP53) replacement therapy has shown promising results in cancer gene therapy. However, it has been hampered, mostly because of the gene delivery vector of choice. CRISPR-Cas9 technology (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) can knock out th...

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Detalles Bibliográficos
Autores principales: Yang Zhou, Jordi, Suwan, Keittisak, Hajitou, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290871/
https://www.ncbi.nlm.nih.gov/pubmed/32429407
http://dx.doi.org/10.3390/jcm9051498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290871/
https://www.ncbi.nlm.nih.gov/pubmed/32429407
http://dx.doi.org/10.3390/jcm9051498

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