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Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt

Astroviruses belong to Astroviridae family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild birds are considered among the natural reservoirs for astroviruses. Infections in humans are associated with severe gastroenteriti...

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Autores principales: El Taweel, Ahmed, Kandeil, Ahmed, Barakat, Ahmed, Alfaroq Rabiee, Omar, Kayali, Ghazi, Ali, Mohamed Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290939/
https://www.ncbi.nlm.nih.gov/pubmed/32357556
http://dx.doi.org/10.3390/v12050485
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author El Taweel, Ahmed
Kandeil, Ahmed
Barakat, Ahmed
Alfaroq Rabiee, Omar
Kayali, Ghazi
Ali, Mohamed Ahmed
author_facet El Taweel, Ahmed
Kandeil, Ahmed
Barakat, Ahmed
Alfaroq Rabiee, Omar
Kayali, Ghazi
Ali, Mohamed Ahmed
author_sort El Taweel, Ahmed
collection PubMed
description Astroviruses belong to Astroviridae family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild birds are considered among the natural reservoirs for astroviruses. Infections in humans are associated with severe gastroenteritis, especially among children. We conducted surveillance for astroviruses in bats, wild birds, and humans in Egypt. Our results indicated relatively high prevalence of astroviruses in those hosts. Phylogenetic analysis revealed diversity of these viruses within hosts. Detected human viruses showed similarity with classic and variant human astroviruses, as well as similarity with animal-origin viruses. Viruses in bats were dispersed, with similarities to other bat viruses as well as other mammalian, including human, viruses. Wild bird viruses varied and were related to other avastroviruses, as well as human astroviruses. Our results indicate that astroviruses are common in bats, wild birds, and humans in Egypt, with a wide gene pool. Potential cross-species transmission may be occurring but should be verified by further surveillance and molecular studies.
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spelling pubmed-72909392020-06-17 Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt El Taweel, Ahmed Kandeil, Ahmed Barakat, Ahmed Alfaroq Rabiee, Omar Kayali, Ghazi Ali, Mohamed Ahmed Viruses Communication Astroviruses belong to Astroviridae family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild birds are considered among the natural reservoirs for astroviruses. Infections in humans are associated with severe gastroenteritis, especially among children. We conducted surveillance for astroviruses in bats, wild birds, and humans in Egypt. Our results indicated relatively high prevalence of astroviruses in those hosts. Phylogenetic analysis revealed diversity of these viruses within hosts. Detected human viruses showed similarity with classic and variant human astroviruses, as well as similarity with animal-origin viruses. Viruses in bats were dispersed, with similarities to other bat viruses as well as other mammalian, including human, viruses. Wild bird viruses varied and were related to other avastroviruses, as well as human astroviruses. Our results indicate that astroviruses are common in bats, wild birds, and humans in Egypt, with a wide gene pool. Potential cross-species transmission may be occurring but should be verified by further surveillance and molecular studies. MDPI 2020-04-26 /pmc/articles/PMC7290939/ /pubmed/32357556 http://dx.doi.org/10.3390/v12050485 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
El Taweel, Ahmed
Kandeil, Ahmed
Barakat, Ahmed
Alfaroq Rabiee, Omar
Kayali, Ghazi
Ali, Mohamed Ahmed
Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt
title Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt
title_full Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt
title_fullStr Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt
title_full_unstemmed Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt
title_short Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt
title_sort diversity of astroviruses circulating in humans, bats, and wild birds in egypt
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290939/
https://www.ncbi.nlm.nih.gov/pubmed/32357556
http://dx.doi.org/10.3390/v12050485
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