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Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt
Astroviruses belong to Astroviridae family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild birds are considered among the natural reservoirs for astroviruses. Infections in humans are associated with severe gastroenteriti...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290939/ https://www.ncbi.nlm.nih.gov/pubmed/32357556 http://dx.doi.org/10.3390/v12050485 |
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author | El Taweel, Ahmed Kandeil, Ahmed Barakat, Ahmed Alfaroq Rabiee, Omar Kayali, Ghazi Ali, Mohamed Ahmed |
author_facet | El Taweel, Ahmed Kandeil, Ahmed Barakat, Ahmed Alfaroq Rabiee, Omar Kayali, Ghazi Ali, Mohamed Ahmed |
author_sort | El Taweel, Ahmed |
collection | PubMed |
description | Astroviruses belong to Astroviridae family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild birds are considered among the natural reservoirs for astroviruses. Infections in humans are associated with severe gastroenteritis, especially among children. We conducted surveillance for astroviruses in bats, wild birds, and humans in Egypt. Our results indicated relatively high prevalence of astroviruses in those hosts. Phylogenetic analysis revealed diversity of these viruses within hosts. Detected human viruses showed similarity with classic and variant human astroviruses, as well as similarity with animal-origin viruses. Viruses in bats were dispersed, with similarities to other bat viruses as well as other mammalian, including human, viruses. Wild bird viruses varied and were related to other avastroviruses, as well as human astroviruses. Our results indicate that astroviruses are common in bats, wild birds, and humans in Egypt, with a wide gene pool. Potential cross-species transmission may be occurring but should be verified by further surveillance and molecular studies. |
format | Online Article Text |
id | pubmed-7290939 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72909392020-06-17 Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt El Taweel, Ahmed Kandeil, Ahmed Barakat, Ahmed Alfaroq Rabiee, Omar Kayali, Ghazi Ali, Mohamed Ahmed Viruses Communication Astroviruses belong to Astroviridae family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild birds are considered among the natural reservoirs for astroviruses. Infections in humans are associated with severe gastroenteritis, especially among children. We conducted surveillance for astroviruses in bats, wild birds, and humans in Egypt. Our results indicated relatively high prevalence of astroviruses in those hosts. Phylogenetic analysis revealed diversity of these viruses within hosts. Detected human viruses showed similarity with classic and variant human astroviruses, as well as similarity with animal-origin viruses. Viruses in bats were dispersed, with similarities to other bat viruses as well as other mammalian, including human, viruses. Wild bird viruses varied and were related to other avastroviruses, as well as human astroviruses. Our results indicate that astroviruses are common in bats, wild birds, and humans in Egypt, with a wide gene pool. Potential cross-species transmission may be occurring but should be verified by further surveillance and molecular studies. MDPI 2020-04-26 /pmc/articles/PMC7290939/ /pubmed/32357556 http://dx.doi.org/10.3390/v12050485 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication El Taweel, Ahmed Kandeil, Ahmed Barakat, Ahmed Alfaroq Rabiee, Omar Kayali, Ghazi Ali, Mohamed Ahmed Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt |
title | Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt |
title_full | Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt |
title_fullStr | Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt |
title_full_unstemmed | Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt |
title_short | Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt |
title_sort | diversity of astroviruses circulating in humans, bats, and wild birds in egypt |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290939/ https://www.ncbi.nlm.nih.gov/pubmed/32357556 http://dx.doi.org/10.3390/v12050485 |
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