Cognitive Decline in Alzheimer’s Disease: Limited Clinical Utility for GWAS or Polygenic Risk Scores in a Clinical Trial Setting

Introduction: Alzheimer’s disease (AD) is a progressive and irreversible neurological disease. The genetics and molecular mechanisms underpinning differential cognitive decline in AD are not well understood; the genetics of AD risk have been studied far more assiduously. Materials and Methods: Two p...

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Detalles Bibliográficos
Autores principales: Euesden, Jack, Gowrisankar, Sivakumar, Qu, Angela Xiaoyan, St. Jean, Pamela, Hughes, Arlene R., Pulford, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290959/
https://www.ncbi.nlm.nih.gov/pubmed/32370229
http://dx.doi.org/10.3390/genes11050501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290959/
https://www.ncbi.nlm.nih.gov/pubmed/32370229
http://dx.doi.org/10.3390/genes11050501

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