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Activated Cardiac Fibroblasts Control Contraction of Human Fibrotic Cardiac Microtissues by a β-Adrenoreceptor-Dependent Mechanism

Cardiac fibrosis represents a serious clinical problem. Development of novel treatment strategies is currently restricted by the lack of the relevant experimental models in a human genetic context. In this study, we fabricated self-aggregating, scaffold-free, 3D cardiac microtissues using human indu...

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Detalles Bibliográficos
Autores principales: Błyszczuk, Przemysław, Zuppinger, Christian, Costa, Ana, Nurzynska, Daria, Di Meglio, Franca, Stellato, Mara, Agarkova, Irina, Smith, Godfrey L., Distler, Oliver, Kania, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290967/
https://www.ncbi.nlm.nih.gov/pubmed/32443848
http://dx.doi.org/10.3390/cells9051270