Cargando…

Allogeneic ADSCs Induce the Production of Alloreactive Memory-CD8 T Cells through HLA-ABC Antigens

We investigated the immunogenicity of allogeneic human adipose-derived mesenchymal stem cells (ADSCs) through the production of alloreactive-CD8 T and -memory CD8 T cells, based on their human leukocyte antigen (HLA) expression. In surface antigen analysis, ADSCs do not express co-stimulatory molecu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Sung-Ho, Kim, Hyun Je, Park, Chung-Gyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290988/ https://www.ncbi.nlm.nih.gov/pubmed/32443511 http://dx.doi.org/10.3390/cells9051246

Ejemplares similares

Allogeneic ADSCs induce CD8 T cell-mediated cytotoxicity and faster cell death after exposure to xenogeneic serum or proinflammatory cytokines
por: Chang, Sung-Ho, et al.
Publicado: (2019)

Alloreactive cytolytic T cell clones with dual recognition of HLA-B27 and HLA-DR2 antigens. Selective involvement of CD8 in their class I-- directed cytotoxicity
Publicado: (1987)

Geometric Analysis of Alloreactive HLA α-Helices
por: Ribarics, Reiner, et al.
Publicado: (2014)

Corecognition of HLA-A1 and HLA-DPw3 by a human CD4+ alloreactive T lymphocyte clone
Publicado: (1990)

CD8+ T-Cell Repertoire in Human Leukocyte Antigen Class I-Mismatched Alloreactive Immune Response
por: Bettens, Florence, et al.
Publicado: (2021)

Responder T cells depleted of alloreactive cells react to antigen presented on allogeneic macrophages from nonresponder strains
Publicado: (1981)

Alloreactive T Cell Receptor Diversity against Structurally Similar or Dissimilar HLA-DP Antigens Assessed by Deep Sequencing
por: Arrieta-Bolaños, Esteban, et al.
Publicado: (2018)

An Antigen-Presenting and Apoptosis-Inducing Polymer Microparticle Prolongs Alloskin Graft Survival by Selectively and Markedly Depleting Alloreactive CD8(+) T Cells
por: Wang, Wei, et al.
Publicado: (2017)

In silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem-Cell Transplant Donors and Recipients: Understanding the Quantitative Immunobiology of Allogeneic Transplantation
por: Jameson-Lee, Max, et al.
Publicado: (2014)

Hidden Patterns of Anti-HLA Class I Alloreactivity Revealed Through Machine Learning
por: Vittoraki, Angeliki G., et al.
Publicado: (2021)

Self H-2 antigens influence the specificity of alloreactive cells
Publicado: (1980)

Alloreactivity of Allogeneic Mesenchymal Stem/Stromal Cells and Other Cellular Therapies: A Concise Review
por: Shah, Kiran, et al.
Publicado: (2022)

GITR Activation Induces an Opposite Effect on Alloreactive CD4(+) and CD8(+) T Cells in Graft-Versus-Host Disease
por: Muriglan, Stephanie J., et al.
Publicado: (2004)

Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B
por: Lewinsohn, Deborah A, et al.
Publicado: (2007)

Direct evidence for binding of CD8 to HLA class I antigens
Publicado: (1989)

Cytomegalovirus induces HLA-class-II-restricted alloreactivity in an acute myeloid leukemia cell line
por: Koldehoff, Michael, et al.
Publicado: (2018)

Silencing of HLA class I on primary human hepatocytes as a novel strategy for reduction in alloreactivity
por: Figueiredo, Constança, et al.
Publicado: (2019)

Sequence homology between HLA-bound cytomegalovirus and human peptides: A potential trigger for alloreactivity
por: Hall, Charles E., et al.
Publicado: (2017)

Predicting Alloreactivity in Transplantation
por: Geneugelijk, Kirsten, et al.
Publicado: (2014)

Preclinical Evaluation of the Safety and Immunological Action of Allogeneic ADSC-Collagen Scaffolds in the Treatment of Chronic Ischemic Cardiomyopathy
por: López-Díaz de Cerio, Ascensión, et al.
Publicado: (2021)

Application of Allogeneic Bone Marrow Cells in View of Residual Alloreactivity: Sirolimus but Not Cyclosporine Evolves Tolerogenic Properties
por: Timrott, Kai, et al.
Publicado: (2015)

Genetic engineering strategies to enhance antitumor reactivity and reduce alloreactivity for allogeneic cell-based cancer therapy
por: Chen, Yuning, et al.
Publicado: (2023)

NK Cell Alloreactivity against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous iPSCs
por: Ichise, Hiroshi, et al.
Publicado: (2017)

Fine-tuning alloreactivity against HLA-DP to control leukemia with tolerable graft-versus-host disease
por: Pidala, Joseph, et al.
Publicado: (2022)

Antigen-specific CD8+ memory stem T cells generated from human peripheral blood effectively eradicate allogeneic targets in mice
por: Guan, Liping, et al.
Publicado: (2018)

Alloreactivity-Based Medical Conditions
por: Vukmanovic, Stanislav, et al.
Publicado: (2013)

Metabolic Pathways in Alloreactive T Cells
por: Brown, Rebecca A., et al.
Publicado: (2020)

Screening self-peptides for recognition by mouse alloreactive CD8(+) T cells using direct ex vivo multimer staining
por: Son, Eric T., et al.
Publicado: (2022)

HLA Class I Molecules as Immune Checkpoints for NK Cell Alloreactivity and Anti-Viral Immunity in Kidney Transplantation
por: Duygu, Burcu, et al.
Publicado: (2021)

HLA-E–dependent Presentation of Mtb-derived Antigen to Human CD8(+) T Cells
por: Heinzel, Amy S., et al.
Publicado: (2002)

CD103 Deficiency Prevents Graft-versus-Host Disease but Spares Graft-versus-Tumor Effects Mediated by Alloreactive CD8 T Cells
por: Liu, Kechang, et al.
Publicado: (2011)

CD4+ T-cell alloreactivity after haploidentical hematopoietic stem cell transplantation
por: Kalin, Burak, et al.
Publicado: (2020)

Cross-Reactivity of Virus-Specific CD8+ T Cells Against Allogeneic HLA-C: Possible Implications for Pregnancy Outcome
por: van der Zwan, Anita, et al.
Publicado: (2018)

The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens
por: Burakoff, SJ, et al.
Publicado: (1978)

Antigen and Memory CD8 T Cells: Were They Both Right?
por: Epelman, Slava, et al.
Publicado: (2007)

Signals for antigen-independent differentiation of memory CD8(+) T cells
por: Kwesi-Maliepaard, Eliza Mari, et al.
Publicado: (2021)

Application of ADSCs and their Exosomes in Scar Prevention
por: Li, Cong, et al.
Publicado: (2021)

The sorafenib anti-relapse effect after alloHSCT is associated with heightened alloreactivity and accumulation of CD8+PD-1+ (CD279+) lymphocytes in marrow
por: Lange, Andrzej, et al.
Publicado: (2018)

On the nature of peptides involved in T cell alloreactivity
Publicado: (1991)

Ischemia augments alloimmune injury through IL-6-driven CD4(+) alloreactivity
por: Uehara, Mayuko, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9nevchcgqlpdr4t8jneto8ghmk