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Genetic and Epigenetic Modification of Rat Liver Progenitor Cells via HNF4α Transduction and 5’ Azacytidine Treatment: An Integrated miRNA and mRNA Expression Profile Analysis

Neonatal liver-derived rat epithelial cells (rLEC) from biliary origin are liver progenitor cells that acquire a hepatocyte-like phenotype upon sequential exposure to hepatogenic growth factors and cytokines. Undifferentiated rLEC express several liver-enriched transcription factors, including the h...

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Detalles Bibliográficos
Autores principales:	Bolleyn, Jennifer, Rombaut, Matthias, Nair, Nisha, Branson, Steven, Heymans, Anja, Chuah, Marinee, VandenDriessche, Thierry, Rogiers, Vera, De Kock, Joery, Vanhaecke, Tamara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291069/ https://www.ncbi.nlm.nih.gov/pubmed/32365562 http://dx.doi.org/10.3390/genes11050486

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