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The Influence of Bariatric Surgery on Pregnancy and Perinatal Outcomes—A Case-Control Study

Introduction: Obesity in pregnant women increases the incidence of pregnancy-induced comorbidities and the rate of operative deliveries. Purpose of the Study: As bariatric surgery is the reference method of treatment of obesity, we wanted to evaluate its influence on the course of pregnancy and peri...

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Autores principales: Różańska-Walędziak, Anna, Walędziak, Maciej, Bartnik, Paweł, Kacperczyk-Bartnik, Joanna, Janik, Michał, Kowalewski, Piotr, Kwiatkowski, Andrzej, Czajkowski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291074/
https://www.ncbi.nlm.nih.gov/pubmed/32370300
http://dx.doi.org/10.3390/jcm9051324
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author Różańska-Walędziak, Anna
Walędziak, Maciej
Bartnik, Paweł
Kacperczyk-Bartnik, Joanna
Janik, Michał
Kowalewski, Piotr
Kwiatkowski, Andrzej
Czajkowski, Krzysztof
author_facet Różańska-Walędziak, Anna
Walędziak, Maciej
Bartnik, Paweł
Kacperczyk-Bartnik, Joanna
Janik, Michał
Kowalewski, Piotr
Kwiatkowski, Andrzej
Czajkowski, Krzysztof
author_sort Różańska-Walędziak, Anna
collection PubMed
description Introduction: Obesity in pregnant women increases the incidence of pregnancy-induced comorbidities and the rate of operative deliveries. Purpose of the Study: As bariatric surgery is the reference method of treatment of obesity, we wanted to evaluate its influence on the course of pregnancy and perinatal outcomes. Material and Methods: Data was collected from 627 female patients after bariatric surgery, of whom 107 had a history of pregnancy after the surgery, and 345 non-bariatric patients who had a delivery at a tertiary perinatal center. Sixty-one cases were matched (1:1) with controls for age, pre-pregnancy BMI and presence of pre-pregnancy comorbidities. The main endpoints were gestational diabetes mellitus (GDM), pregnancy-induced hypertension (PIH), small (SGA) and large for gestational age infants (LGA) and cesarean sections (CS). Results: Patients after bariatric procedures were significantly less likely to have GDM (19.67%/37.7%; p = 0.0433), PIH (11.47%/16.39%; p = 0.6072) and preterm delivery (13.11%/37.7%; p = 0.0026). The CS rate was higher (57.38%/40.98%; p = 0.0987). There was an increased risk of SGA (18.03%/13.11%; p = 0.6072) and a decreased risk of LGA (6.56%/16.39%; p = 0.146). Conclusions: Patients after bariatric surgery have a decreased risk of pregnancy-induced comorbidities, preterm deliveries and LGA infants, with an increase in rate of CS and SGA infants compared to general population matched for pre-pregnancy BMI, age and presence of pre-pregnancy comorbidities.
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spelling pubmed-72910742020-06-17 The Influence of Bariatric Surgery on Pregnancy and Perinatal Outcomes—A Case-Control Study Różańska-Walędziak, Anna Walędziak, Maciej Bartnik, Paweł Kacperczyk-Bartnik, Joanna Janik, Michał Kowalewski, Piotr Kwiatkowski, Andrzej Czajkowski, Krzysztof J Clin Med Article Introduction: Obesity in pregnant women increases the incidence of pregnancy-induced comorbidities and the rate of operative deliveries. Purpose of the Study: As bariatric surgery is the reference method of treatment of obesity, we wanted to evaluate its influence on the course of pregnancy and perinatal outcomes. Material and Methods: Data was collected from 627 female patients after bariatric surgery, of whom 107 had a history of pregnancy after the surgery, and 345 non-bariatric patients who had a delivery at a tertiary perinatal center. Sixty-one cases were matched (1:1) with controls for age, pre-pregnancy BMI and presence of pre-pregnancy comorbidities. The main endpoints were gestational diabetes mellitus (GDM), pregnancy-induced hypertension (PIH), small (SGA) and large for gestational age infants (LGA) and cesarean sections (CS). Results: Patients after bariatric procedures were significantly less likely to have GDM (19.67%/37.7%; p = 0.0433), PIH (11.47%/16.39%; p = 0.6072) and preterm delivery (13.11%/37.7%; p = 0.0026). The CS rate was higher (57.38%/40.98%; p = 0.0987). There was an increased risk of SGA (18.03%/13.11%; p = 0.6072) and a decreased risk of LGA (6.56%/16.39%; p = 0.146). Conclusions: Patients after bariatric surgery have a decreased risk of pregnancy-induced comorbidities, preterm deliveries and LGA infants, with an increase in rate of CS and SGA infants compared to general population matched for pre-pregnancy BMI, age and presence of pre-pregnancy comorbidities. MDPI 2020-05-02 /pmc/articles/PMC7291074/ /pubmed/32370300 http://dx.doi.org/10.3390/jcm9051324 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Różańska-Walędziak, Anna
Walędziak, Maciej
Bartnik, Paweł
Kacperczyk-Bartnik, Joanna
Janik, Michał
Kowalewski, Piotr
Kwiatkowski, Andrzej
Czajkowski, Krzysztof
The Influence of Bariatric Surgery on Pregnancy and Perinatal Outcomes—A Case-Control Study
title The Influence of Bariatric Surgery on Pregnancy and Perinatal Outcomes—A Case-Control Study
title_full The Influence of Bariatric Surgery on Pregnancy and Perinatal Outcomes—A Case-Control Study
title_fullStr The Influence of Bariatric Surgery on Pregnancy and Perinatal Outcomes—A Case-Control Study
title_full_unstemmed The Influence of Bariatric Surgery on Pregnancy and Perinatal Outcomes—A Case-Control Study
title_short The Influence of Bariatric Surgery on Pregnancy and Perinatal Outcomes—A Case-Control Study
title_sort influence of bariatric surgery on pregnancy and perinatal outcomes—a case-control study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291074/
https://www.ncbi.nlm.nih.gov/pubmed/32370300
http://dx.doi.org/10.3390/jcm9051324
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