Nearly Complete Genome Sequence of Brugia malayi Strain FR3

Lymphatic filariasis affects ∼120 million people and can result in elephantiasis and hydrocele. Here, we report the nearly complete genome sequence of the best-studied causative agent of lymphatic filariasis, Brugia malayi. The assembly contains four autosomes, an X chromosome, and only eight gaps b...

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Detalles Bibliográficos
Autores principales: Tracey, Alan, Foster, Jeremy M., Paulini, Michael, Grote, Alexandra, Mattick, John, Tsai, Yu-Chih, Chung, Matthew, Cotton, James A., Clark, Tyson A., Geber, Adam, Holroyd, Nancy, Korlach, Jonas, Libro, Silvia, Lustigman, Sara, Michalski, Michelle L., Rogers, Matthew B., Twaddle, Alan, Dunning Hotopp, Julie C., Berriman, Matthew, Ghedin, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291094/
https://www.ncbi.nlm.nih.gov/pubmed/32527783
http://dx.doi.org/10.1128/MRA.00154-20
Descripción
Sumario:Lymphatic filariasis affects ∼120 million people and can result in elephantiasis and hydrocele. Here, we report the nearly complete genome sequence of the best-studied causative agent of lymphatic filariasis, Brugia malayi. The assembly contains four autosomes, an X chromosome, and only eight gaps but lacks a contiguous sequence for the known Y chromosome.

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