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The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse Alzheimer’s Disease Models

Brains that are affected by Alzheimer’s disease (AD) are characterized by the overload of extracellular amyloid β (Aβ) peptides, but recent data from cellular and animal models propose that Aβ deposition is preceded by intraneuronal accumulation of the direct precursor of Aβ, C99. These studies indi...

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Detalles Bibliográficos
Autores principales:	Bécot, Anaïs, Pardossi-Piquard, Raphaëlle, Bourgeois, Alexandre, Duplan, Eric, Xiao, Qingli, Diwan, Abhinav, Lee, Jin-Moo, Lauritzen, Inger, Checler, Frédéric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291113/ https://www.ncbi.nlm.nih.gov/pubmed/32408680 http://dx.doi.org/10.3390/cells9051204

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