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Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults

This study aimed to assess the effects of a multicomponent exercise program on physical function and muscle mass in older adults with sarcopenia or pre-sarcopenia. Moreover, we aim to standardize the exercise program for easy incorporation in the daily life of community-dwelling older adults as a se...

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Autores principales: Makizako, Hyuma, Nakai, Yuki, Tomioka, Kazutoshi, Taniguchi, Yoshiaki, Sato, Nana, Wada, Ayumi, Kiyama, Ryoji, Tsutsumimoto, Kota, Ohishi, Mitsuru, Kiuchi, Yuto, Kubozono, Takuro, Takenaka, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291119/
https://www.ncbi.nlm.nih.gov/pubmed/32397192
http://dx.doi.org/10.3390/jcm9051386
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author Makizako, Hyuma
Nakai, Yuki
Tomioka, Kazutoshi
Taniguchi, Yoshiaki
Sato, Nana
Wada, Ayumi
Kiyama, Ryoji
Tsutsumimoto, Kota
Ohishi, Mitsuru
Kiuchi, Yuto
Kubozono, Takuro
Takenaka, Toshihiro
author_facet Makizako, Hyuma
Nakai, Yuki
Tomioka, Kazutoshi
Taniguchi, Yoshiaki
Sato, Nana
Wada, Ayumi
Kiyama, Ryoji
Tsutsumimoto, Kota
Ohishi, Mitsuru
Kiuchi, Yuto
Kubozono, Takuro
Takenaka, Toshihiro
author_sort Makizako, Hyuma
collection PubMed
description This study aimed to assess the effects of a multicomponent exercise program on physical function and muscle mass in older adults with sarcopenia or pre-sarcopenia. Moreover, we aim to standardize the exercise program for easy incorporation in the daily life of community-dwelling older adults as a secondary outcome. A single-blind randomized controlled trial was conducted with individuals (≥60 years) who had sarcopenia or pre-sarcopenia (n = 72). Participants were randomly assigned to the exercise and control groups. The exercise program consisted of 12 weekly 60-min sessions that included resistance, balance, flexibility, and aerobic training. Outcome measures were physical function and muscle mass. Assessments were conducted before and immediately after the intervention. Among the 72 participants (mean age: 75.0 ± 6.9 years; 70.8% women), 67 (93.1%) completed the trial. Group-by-time interactions on the chair stand (p = 0.02) and timed “up and go” (p = 0.01) tests increased significantly in the exercise group. Although the exercise group showed a tendency to prevent loss of muscle mass, no significant interaction effects were observed for cross-sectional muscle area and muscle volume. The 12-week exercise program improved physical function in the intervention group. Although it is unclear whether the program is effective in increasing muscle mass, a multicomponent exercise program would be an effective treatment for physical function among older adults with sarcopenia.
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spelling pubmed-72911192020-06-17 Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults Makizako, Hyuma Nakai, Yuki Tomioka, Kazutoshi Taniguchi, Yoshiaki Sato, Nana Wada, Ayumi Kiyama, Ryoji Tsutsumimoto, Kota Ohishi, Mitsuru Kiuchi, Yuto Kubozono, Takuro Takenaka, Toshihiro J Clin Med Article This study aimed to assess the effects of a multicomponent exercise program on physical function and muscle mass in older adults with sarcopenia or pre-sarcopenia. Moreover, we aim to standardize the exercise program for easy incorporation in the daily life of community-dwelling older adults as a secondary outcome. A single-blind randomized controlled trial was conducted with individuals (≥60 years) who had sarcopenia or pre-sarcopenia (n = 72). Participants were randomly assigned to the exercise and control groups. The exercise program consisted of 12 weekly 60-min sessions that included resistance, balance, flexibility, and aerobic training. Outcome measures were physical function and muscle mass. Assessments were conducted before and immediately after the intervention. Among the 72 participants (mean age: 75.0 ± 6.9 years; 70.8% women), 67 (93.1%) completed the trial. Group-by-time interactions on the chair stand (p = 0.02) and timed “up and go” (p = 0.01) tests increased significantly in the exercise group. Although the exercise group showed a tendency to prevent loss of muscle mass, no significant interaction effects were observed for cross-sectional muscle area and muscle volume. The 12-week exercise program improved physical function in the intervention group. Although it is unclear whether the program is effective in increasing muscle mass, a multicomponent exercise program would be an effective treatment for physical function among older adults with sarcopenia. MDPI 2020-05-08 /pmc/articles/PMC7291119/ /pubmed/32397192 http://dx.doi.org/10.3390/jcm9051386 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Makizako, Hyuma
Nakai, Yuki
Tomioka, Kazutoshi
Taniguchi, Yoshiaki
Sato, Nana
Wada, Ayumi
Kiyama, Ryoji
Tsutsumimoto, Kota
Ohishi, Mitsuru
Kiuchi, Yuto
Kubozono, Takuro
Takenaka, Toshihiro
Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults
title Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults
title_full Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults
title_fullStr Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults
title_full_unstemmed Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults
title_short Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults
title_sort effects of a multicomponent exercise program in physical function and muscle mass in sarcopenic/pre-sarcopenic adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291119/
https://www.ncbi.nlm.nih.gov/pubmed/32397192
http://dx.doi.org/10.3390/jcm9051386
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