Rous Sarcoma Virus Genomic RNA Dimerization Capability In Vitro Is Not a Prerequisite for Viral Infectivity

Retroviruses package their full-length, dimeric genomic RNA (gRNA) via specific interactions between the Gag polyprotein and a “Ψ” packaging signal located in the gRNA 5′-UTR. Rous sarcoma virus (RSV) gRNA has a contiguous, well-defined Ψ element, that directs the packaging of heterologous RNAs effi...

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Detalles Bibliográficos
Autores principales: Liu, Shuohui, Kaddis Maldonado, Rebecca, Rye-McCurdy, Tiffiny, Binkley, Christiana, Bah, Aissatou, Chen, Eunice C., Rice, Breanna L., Parent, Leslie J., Musier-Forsyth, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291142/
https://www.ncbi.nlm.nih.gov/pubmed/32455905
http://dx.doi.org/10.3390/v12050568

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