Telomere and Centromere Staining Followed by M-FISH Improves Diagnosis of Chromosomal Instability and Its Clinical Utility

Dicentric chromosomes are a relevant marker of chromosomal instability. Their appearance is associated with telomere dysfunction, leading to cancer progression and a poor clinical outcome. Here, we present Telomere and Centromere staining followed by M-FISH (TC+M-FISH) for improved detection of telo...

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Detalles Bibliográficos
Autores principales: M’kacher, Radhia, Colicchio, Bruno, Borie, Claire, Junker, Steffen, Marquet, Valentine, Heidingsfelder, Leonhard, Soehnlen, Kevin, Najar, Wala, Hempel, William M., Oudrhiri, Noufissa, Wilhelm-Murer, Nadège, Miguet, Marguerite, Arnoux, Micheline, Ferrapie, Catherine, Kerbrat, Wendy, Plesch, Andreas, Dieterlen, Alain, Girinsky, Theodore, Voisin, Philippe, Deschenes, Georges, Tabet, Anne-Claude, Yardin, Catherine, Bennaceur-Griscelli, Annelise, Fenech, Michael, Carde, Patrice, Jeandidier, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291161/
https://www.ncbi.nlm.nih.gov/pubmed/32349350
http://dx.doi.org/10.3390/genes11050475

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