The Self-Assembly of a Cyclometalated Palladium Photosensitizer into Protein-Stabilized Nanorods Triggers Drug Uptake In Vitro and In Vivo

[Image: see text] Enhanced passive diffusion is usually considered to be the primary cause of the enhanced cellular uptake of cyclometalated drugs because cyclometalation lowers the charge of a metal complex and increases its lipophilicity. However, in this work, monocationic cyclometalated palladiu...

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Detalles Bibliográficos
Autores principales: Zhou, Xue-Quan, Xiao, Ming, Ramu, Vadde, Hilgendorf, Jonathan, Li, Xuezhao, Papadopoulou, Panagiota, Siegler, Maxime A., Kros, Alexander, Sun, Wen, Bonnet, Sylvestre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291344/
https://www.ncbi.nlm.nih.gov/pubmed/32378894
http://dx.doi.org/10.1021/jacs.0c01369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291344/
https://www.ncbi.nlm.nih.gov/pubmed/32378894
http://dx.doi.org/10.1021/jacs.0c01369

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