Cargando…
The Self-Assembly of a Cyclometalated Palladium Photosensitizer into Protein-Stabilized Nanorods Triggers Drug Uptake In Vitro and In Vivo
[Image: see text] Enhanced passive diffusion is usually considered to be the primary cause of the enhanced cellular uptake of cyclometalated drugs because cyclometalation lowers the charge of a metal complex and increases its lipophilicity. However, in this work, monocationic cyclometalated palladiu...
Autores principales: | Zhou, Xue-Quan, Xiao, Ming, Ramu, Vadde, Hilgendorf, Jonathan, Li, Xuezhao, Papadopoulou, Panagiota, Siegler, Maxime A., Kros, Alexander, Sun, Wen, Bonnet, Sylvestre |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291344/ https://www.ncbi.nlm.nih.gov/pubmed/32378894 http://dx.doi.org/10.1021/jacs.0c01369 |
Ejemplares similares
-
Rollover Cyclometalation vs Nitrogen Coordination
in Tetrapyridyl Anticancer Gold(III) Complexes: Effect on Protein
Interaction and Toxicity
por: Zhou, Xue-Quan, et al.
Publicado: (2021) -
In vivo metallophilic self-assembly of a light-activated anticancer drug
por: Zhou, Xue-Quan, et al.
Publicado: (2023) -
Selective Preparation of a Heteroleptic Cyclometallated Ruthenium Complex Capable of Undergoing Photosubstitution of a Bidentate Ligand
por: Cuello‐Garibo, Jordi‐Amat, et al.
Publicado: (2018) -
Photochemical
Resolution of a Thermally Inert Cyclometalated
Ru(phbpy)(N–N)(Sulfoxide)(+) Complex
por: Lameijer, Lucien N., et al.
Publicado: (2018) -
TLD1433 Photosensitizer Inhibits Conjunctival Melanoma Cells in Zebrafish Ectopic and Orthotopic Tumour Models
por: Chen, Quanchi, et al.
Publicado: (2020)