Cargando…
Novel Quinazolin-2,4-Dione Hybrid Molecules as Possible Inhibitors Against Malaria: Synthesis and in silico Molecular Docking Studies
The research explores the synthesis of a series of novel hybrid quinazolin-2,4-dione analogs bearing acetyl/amide bridged-nitrogen heterocyclic moieties such as azetidinone, pyrrole, oxazole, oxadiazole, thiazole, pyrazole, and thiazolidine scaffolds 2-16. The newly synthesized compounds were struct...
Autores principales: | Haredi Abdelmonsef, Aboubakr, Eldeeb Mohamed, Mahmoud, El-Naggar, Mohamed, Temairk, Hussain, Mohamed Mosallam, Ahmed |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291371/ https://www.ncbi.nlm.nih.gov/pubmed/32582763 http://dx.doi.org/10.3389/fmolb.2020.00105 |
Ejemplares similares
-
Synthesis, Characterization, Antibacterial Activity, and Computer-Aided Design of Novel Quinazolin-2,4-dione Derivatives as Potential Inhibitors Against Vibrio cholerae
por: El-Naggar, Mohamed, et al.
Publicado: (2020) -
Design and biological evaluation of 3-substituted quinazoline-2,4(1H,3H)-dione derivatives as dual c-Met/VEGFR-2-TK inhibitors
por: Hassan, Abdelfattah, et al.
Publicado: (2023) -
Cyclization of
Chalcone Derivatives: Design, Synthesis, In Silico Docking Study, and Biological Evaluation of New
Quinazolin-2,4-diones Incorporating Five-, Six-, and
Seven-Membered Ring Moieties as Potent Antibacterial Inhibitors
por: El-Naggar, Mohamed, et al.
Publicado: (2023) -
Design, synthetic approach, in silico molecular docking and antibacterial activity of quinazolin-2,4-dione hybrids bearing bioactive scaffolds
por: Abdelmonsef, Aboubakr H., et al.
Publicado: (2022) -
Synthesis, Molecular Docking Analysis and in Vitro Biological Evaluation of Some New Heterocyclic Scaffolds-Based Indole Moiety as Possible Antimicrobial Agents
por: Hassan, Entesar A., et al.
Publicado: (2022)