Deconvolution of bulk blood eQTL effects into immune cell subpopulations

BACKGROUND: Expression quantitative trait loci (eQTL) studies are used to interpret the function of disease-associated genetic risk factors. To date, most eQTL analyses have been conducted in bulk tissues, such as whole blood and tissue biopsies, which are likely to mask the cell type-context of the...

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Detalles Bibliográficos
Autores principales: Aguirre-Gamboa, Raúl, de Klein, Niek, di Tommaso, Jennifer, Claringbould, Annique, van der Wijst, Monique GP, de Vries, Dylan, Brugge, Harm, Oelen, Roy, Võsa, Urmo, Zorro, Maria M., Chu, Xiaojin, Bakker, Olivier B., Borek, Zuzanna, Ricaño-Ponce, Isis, Deelen, Patrick, Xu, Cheng-Jiang, Swertz, Morris, Jonkers, Iris, Withoff, Sebo, Joosten, Irma, Sanna, Serena, Kumar, Vinod, Koenen, Hans J. P. M., Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Franke, Lude, Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291428/
https://www.ncbi.nlm.nih.gov/pubmed/32532224
http://dx.doi.org/10.1186/s12859-020-03576-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291428/
https://www.ncbi.nlm.nih.gov/pubmed/32532224
http://dx.doi.org/10.1186/s12859-020-03576-5

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