Identification of hub genes associated with RNAi-induced silencing of XIAP through targeted proteomics approach in MCF7 cells

BACKGROUND: The X-linked inhibitor of apoptosis protein (XIAP) is the most potent caspase inhibitor of the IAP family in apoptosis pathway. This study aims to identify the molecular targets of XIAP in human breast cancer cells exposed to XIAP siRNA by proteomics screening. The expression of XIAP was...

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Detalles Bibliográficos
Autores principales: Gholizadeh, Mehdi Agha, Shamsabadi, Fatemeh T., Yamchi, Ahad, Golalipour, Masoud, Jhingan, Gagan Deep, Shahbazi, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291505/
https://www.ncbi.nlm.nih.gov/pubmed/32537125
http://dx.doi.org/10.1186/s13578-020-00437-9

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