Cargando…

A Whole-Brain Cell-Type-Specific Sparse Neuron Labeling Method and Its Application in a Shank3 Autistic Mouse Model

Single neurons, as the basic unit of the brain, consist of a cell body and processes, including dendrites and axons. Even neurons of the same type show various subtle process characteristics to fit into the diverse neural circuits. Different cell types of neurons form complicated circuits in the bra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Di, Ren, Keke, Liu, Haiying, Mao, Honghui, Li, Zongyan, Mo, Huiming, Xie, Shengjun, Shi, Yiwu, Chen, Qian, Wang, Wenting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291601/ https://www.ncbi.nlm.nih.gov/pubmed/32581718 http://dx.doi.org/10.3389/fncel.2020.00145

Ejemplares similares

Dissection of the relationship between anxiety and stereotyped self-grooming using the Shank3B mutant autistic model, acute stress model and chronic pain model
por: Liu, Haiying, et al.
Publicado: (2021)

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction
por: Peça, João, et al.
Publicado: (2011)

Dysfunction of Cortical GABAergic Neurons Leads to Sensory Hyper-reactivity in a Shank3 Mouse Model of ASD
por: Chen, Qian, et al.
Publicado: (2020)

Adult Restoration of Shank3 Expression Rescues Selective Autistic-Like Phenotypes
por: Mei, Yuan, et al.
Publicado: (2016)

Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development
por: Kathuria, A, et al.
Publicado: (2018)

Functional Relevance of Missense Mutations Affecting the N-Terminal Part of Shank3 Found in Autistic Patients
por: Hassani Nia, Fatemeh, et al.
Publicado: (2018)

The Shank3(Venus/Venus) knock in mouse enables isoform-specific functional studies of Shank3a
por: Bouquier, Nathalie, et al.
Publicado: (2022)

New Mouse Lines for the Analysis of Neuronal Morphology Using CreER(T)/loxP-Directed Sparse Labeling
por: Badea, Tudor C., et al.
Publicado: (2009)

Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Autistic-Like Behaviors of SHANK3 Mutant Beagle Dogs
por: Zhao, Lu, et al.
Publicado: (2022)

Distinct Phenotypes of Shank2 Mouse Models Reflect Neuropsychiatric Spectrum Disorders of Human Patients With SHANK2 Variants
por: Eltokhi, Ahmed, et al.
Publicado: (2018)

Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder
por: Lee, Yong-Seok, et al.
Publicado: (2020)

Integrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations
por: Lee, Yeunkum, et al.
Publicado: (2017)

Genetically-Directed, Cell Type-Specific Sparse Labeling for the Analysis of Neuronal Morphology
por: Rotolo, Thomas, et al.
Publicado: (2008)

Altered Light Sensitivity of Circadian Clock in Shank3(+/–) Mouse
por: Alamilla, Javier, et al.
Publicado: (2021)

Sparse postnatal labeling and quantification of superficial cortical cell synapses in the mouse neocortex
por: Gesuita, Lorenzo, et al.
Publicado: (2022)

Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons
por: Ha, Huong T. T., et al.
Publicado: (2018)

Haploinsufficiency of Shank3 increases the orientation selectivity of V1 neurons
por: Ortiz-Cruz, Carlos Alberto, et al.
Publicado: (2022)

William Frederick Shanks
Publicado: (1926)

Excitatory and Inhibitory Synaptic Imbalance Caused by Brain-Derived Neurotrophic Factor Deficits During Development in a Valproic Acid Mouse Model of Autism
por: Qi, Chuchu, et al.
Publicado: (2022)

Neuromotor Development in the Shank3 Mouse Model of Autism Spectrum Disorder
por: Pillerová, Miriam, et al.
Publicado: (2022)

SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice
por: Lutz, Anne-Kathrin, et al.
Publicado: (2021)

An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function
por: Wang, Li, et al.
Publicado: (2019)

A chimeric mouse model to study human iPSC-derived neurons: the case of a truncating SHANK3 mutation
por: Vitrac, Aline, et al.
Publicado: (2020)

Genetically-directed Sparse Neuronal Labeling in BAC Transgenic Mice through Mononucleotide Repeat Frameshift
por: Lu, Xiao-Hong, et al.
Publicado: (2017)

Association study between autistic-like traits and polymorphisms in the autism candidate regions RELN, CNTNAP2, SHANK3, and CDH9/10
por: Jonsson, Lina, et al.
Publicado: (2014)

Pull-off characteristics of double-shanked compared to single-shanked ligation clips: an animal study
por: Schenk, Martin, et al.
Publicado: (2016)

Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice
por: Wang, Xiaoming, et al.
Publicado: (2014)

Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus
por: Heise, Christopher, et al.
Publicado: (2016)

Sparse Density Estimation with Measurement Errors
por: Yang, Xiaowei, et al.
Publicado: (2021)

Whole Genome Sequence of Bacillus velezensis Strain GUMT319: A Potential Biocontrol Agent Against Tobacco Black Shank Disease
por: Ding, Haixia, et al.
Publicado: (2021)

SHANK2 mutations associated with Autism Spectrum Disorder cause hyperconnectivity of human neurons
por: Zaslavsky, Kirill, et al.
Publicado: (2019)

SHANK3 in vagal sensory neurons regulates body temperature, systemic inflammation, and sepsis
por: Zhang, Linlin, et al.
Publicado: (2023)

Downregulation of mGluR1-mediated signaling underlying autistic-like core symptoms in Shank1 P1812L-knock-in mice
por: Qin, Yue, et al.
Publicado: (2023)

Differentially altered social dominance- and cooperative-like behaviors in Shank2- and Shank3-mutant mice
por: Han, Kyung Ah, et al.
Publicado: (2020)

Shank3 deletion in PV neurons is associated with abnormal behaviors and neuronal functions that are rescued by increasing GABAergic signaling
por: Pagano, Jessica, et al.
Publicado: (2023)

Model of a sparse encoding neuron
por: Yenduri, Praveen K, et al.
Publicado: (2012)

Rare SHANK2 variants in schizophrenia
por: Peykov, S, et al.
Publicado: (2015)

Sex Hormones Regulate SHANK Expression
por: Berkel, Simone, et al.
Publicado: (2018)

Restoring Shank3 in the rostral brainstem of shank3ab−/− zebrafish autism models rescues sensory deficits
por: Kozol, Robert A., et al.
Publicado: (2021)

Combining dense and sparse labeling in optical DNA mapping
por: Torstensson, Erik, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6rbmm12lccnhrspebl3pp5reip