Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report

BACKGROUND: Tuberculosis (TB) remains a severe health burden worldwide. The manifestation of concurrent tuberculous cerebral and ocular involvements associated with TB is uncommon. CASE PRESENTATION: We report a 17-year-old girl with concurrent tuberculous cerebral and ocular involvements and visual...

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Autores principales: Zhang, Yan-Kun, Fu, Hong-Yi, Guan, Yan, Li, Yu-Jing, Bai, Hong-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291746/
https://www.ncbi.nlm.nih.gov/pubmed/32532239
http://dx.doi.org/10.1186/s12886-020-01504-y
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author Zhang, Yan-Kun
Fu, Hong-Yi
Guan, Yan
Li, Yu-Jing
Bai, Hong-Zhong
author_facet Zhang, Yan-Kun
Fu, Hong-Yi
Guan, Yan
Li, Yu-Jing
Bai, Hong-Zhong
author_sort Zhang, Yan-Kun
collection PubMed
description BACKGROUND: Tuberculosis (TB) remains a severe health burden worldwide. The manifestation of concurrent tuberculous cerebral and ocular involvements associated with TB is uncommon. CASE PRESENTATION: We report a 17-year-old girl with concurrent tuberculous cerebral and ocular involvements and visual impairment due to choroidal neovascularization. This study emphasizes the definite diagnosis with the combination of ophthalmological examination, multimodal imaging and routine tuberculosis testing, and the proper management with intravitreal anti-VEGF injection accompanied by systemic anti-tuberculosis therapy. CONCLUSION: Combined applications of routine TB tests, fundus multimodal imaging and diagnostic therapy greatly help the clinician to establish a precise diagnosis and in monitoring the therapeutic response.
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spelling pubmed-72917462020-06-12 Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report Zhang, Yan-Kun Fu, Hong-Yi Guan, Yan Li, Yu-Jing Bai, Hong-Zhong BMC Ophthalmol Case Report BACKGROUND: Tuberculosis (TB) remains a severe health burden worldwide. The manifestation of concurrent tuberculous cerebral and ocular involvements associated with TB is uncommon. CASE PRESENTATION: We report a 17-year-old girl with concurrent tuberculous cerebral and ocular involvements and visual impairment due to choroidal neovascularization. This study emphasizes the definite diagnosis with the combination of ophthalmological examination, multimodal imaging and routine tuberculosis testing, and the proper management with intravitreal anti-VEGF injection accompanied by systemic anti-tuberculosis therapy. CONCLUSION: Combined applications of routine TB tests, fundus multimodal imaging and diagnostic therapy greatly help the clinician to establish a precise diagnosis and in monitoring the therapeutic response. BioMed Central 2020-06-12 /pmc/articles/PMC7291746/ /pubmed/32532239 http://dx.doi.org/10.1186/s12886-020-01504-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Zhang, Yan-Kun
Fu, Hong-Yi
Guan, Yan
Li, Yu-Jing
Bai, Hong-Zhong
Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_full Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_fullStr Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_full_unstemmed Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_short Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_sort concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291746/
https://www.ncbi.nlm.nih.gov/pubmed/32532239
http://dx.doi.org/10.1186/s12886-020-01504-y
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