Cargando…
Eye-Light on Age-Related Macular Degeneration: Targeting Nrf2-Pathway as a Novel Therapeutic Strategy for Retinal Pigment Epithelium
Age-related macular degeneration (AMD) is a common disease with a multifactorial aetiology, still lacking effective and curative therapies. Among the early events triggering AMD is the deterioration of the retinal pigment epithelium (RPE), whose fundamental functions assure good health of the retina...
Autores principales: | Catanzaro, Michele, Lanni, Cristina, Basagni, Filippo, Rosini, Michela, Govoni, Stefano, Amadio, Marialaura |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291861/ https://www.ncbi.nlm.nih.gov/pubmed/32581803 http://dx.doi.org/10.3389/fphar.2020.00844 |
Ejemplares similares
-
Targeting Cytokine Release Through the Differential Modulation of Nrf2 and NF-κB Pathways by Electrophilic/Non-Electrophilic Compounds
por: Fagiani, Francesca, et al.
Publicado: (2020) -
Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells
por: Koskela, Ali, et al.
Publicado: (2022) -
A Nature-Inspired Nrf2 Activator Protects Retinal Explants from Oxidative Stress and Neurodegeneration
por: Rossino, Maria Grazia, et al.
Publicado: (2021) -
Modulation of Keap1/Nrf2/ARE Signaling Pathway by Curcuma- and Garlic-Derived Hybrids
por: Serafini, Melania Maria, et al.
Publicado: (2020) -
Automated evaluation of retinal pigment epithelium disease area in eyes with age-related macular degeneration
por: Motozawa, Naohiro, et al.
Publicado: (2022)