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A New Design for the Fixed Primer Regions in an Oligonucleotide Library for SELEX Aptamer Screening
Single-stranded DNA or RNA oligonucleotides, often called aptamers, can bind to a molecular target with both high affinity and selectivity due to their distinct three-dimensional structures. A technique called systematic evolution of ligands by exponential enrichment (SELEX) is used to screen aptame...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291870/ https://www.ncbi.nlm.nih.gov/pubmed/32582641 http://dx.doi.org/10.3389/fchem.2020.00475 |