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Case of atypical femoral fractures that mimicked the typical imaging findings of prostate cancer‐induced bone metastasis

INTRODUCTION: Atypical femoral fractures are atraumatic or minimally traumatic fractures and rare side effects of bone resorption inhibitors. Bone resorption inhibitors are frequently used in the treatment of prostate cancer. CASE PRESENTATION: A 62‐year‐old man complained of difficulty in walking a...

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Autores principales: Nezu, Kunihisa, Endo, Yuji, Katayama, Hiromichi, Nozawa, Yoshihiro, Kyan, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292123/
https://www.ncbi.nlm.nih.gov/pubmed/32743443
http://dx.doi.org/10.1002/iju5.12104
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author Nezu, Kunihisa
Endo, Yuji
Katayama, Hiromichi
Nozawa, Yoshihiro
Kyan, Atsushi
author_facet Nezu, Kunihisa
Endo, Yuji
Katayama, Hiromichi
Nozawa, Yoshihiro
Kyan, Atsushi
author_sort Nezu, Kunihisa
collection PubMed
description INTRODUCTION: Atypical femoral fractures are atraumatic or minimally traumatic fractures and rare side effects of bone resorption inhibitors. Bone resorption inhibitors are frequently used in the treatment of prostate cancer. CASE PRESENTATION: A 62‐year‐old man complained of difficulty in walking and left lower limb pain. Androgen deprivation and denosumab therapy for prostate cancer‐induced bone metastasis was initiated 27 months ago. Even though the prostate‐specific antigen level did not increase, imaging studies indicated the possibility of bone metastasis. The patient underwent bone biopsy; however, no malignancy was detected. Afterward, he had a fall, causing a complete fracture in his left femur. CONCLUSION: Atypical femoral fractures occasionally mimic typical imaging findings and outcomes of bone metastasis. This case is important for recognizing such cases.
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spelling pubmed-72921232020-07-30 Case of atypical femoral fractures that mimicked the typical imaging findings of prostate cancer‐induced bone metastasis Nezu, Kunihisa Endo, Yuji Katayama, Hiromichi Nozawa, Yoshihiro Kyan, Atsushi IJU Case Rep Case Reports INTRODUCTION: Atypical femoral fractures are atraumatic or minimally traumatic fractures and rare side effects of bone resorption inhibitors. Bone resorption inhibitors are frequently used in the treatment of prostate cancer. CASE PRESENTATION: A 62‐year‐old man complained of difficulty in walking and left lower limb pain. Androgen deprivation and denosumab therapy for prostate cancer‐induced bone metastasis was initiated 27 months ago. Even though the prostate‐specific antigen level did not increase, imaging studies indicated the possibility of bone metastasis. The patient underwent bone biopsy; however, no malignancy was detected. Afterward, he had a fall, causing a complete fracture in his left femur. CONCLUSION: Atypical femoral fractures occasionally mimic typical imaging findings and outcomes of bone metastasis. This case is important for recognizing such cases. John Wiley and Sons Inc. 2019-07-04 /pmc/articles/PMC7292123/ /pubmed/32743443 http://dx.doi.org/10.1002/iju5.12104 Text en © 2019 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Urological Association. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Nezu, Kunihisa
Endo, Yuji
Katayama, Hiromichi
Nozawa, Yoshihiro
Kyan, Atsushi
Case of atypical femoral fractures that mimicked the typical imaging findings of prostate cancer‐induced bone metastasis
title Case of atypical femoral fractures that mimicked the typical imaging findings of prostate cancer‐induced bone metastasis
title_full Case of atypical femoral fractures that mimicked the typical imaging findings of prostate cancer‐induced bone metastasis
title_fullStr Case of atypical femoral fractures that mimicked the typical imaging findings of prostate cancer‐induced bone metastasis
title_full_unstemmed Case of atypical femoral fractures that mimicked the typical imaging findings of prostate cancer‐induced bone metastasis
title_short Case of atypical femoral fractures that mimicked the typical imaging findings of prostate cancer‐induced bone metastasis
title_sort case of atypical femoral fractures that mimicked the typical imaging findings of prostate cancer‐induced bone metastasis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292123/
https://www.ncbi.nlm.nih.gov/pubmed/32743443
http://dx.doi.org/10.1002/iju5.12104
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