Ectopic adrenal adenoma causing gross hematuria: Steroidogenic enzyme profiling and literature review

INTRODUCTION: Aberrant cortical adrenal tissues are not generally identified in adults. Herein, we present a very rare case of an ectopic adrenal tumor located in the renal hilum that caused gross hematuria. CASE PRESENTATION: A 33‐year‐old man suddenly presented with asymptomatic gross hematuria. A...

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Detalles Bibliográficos
Autores principales: Ashikari, Daisaku, Tawara, So, Sato, Katsuhiko, Mochida, Junichi, Masuda, Shinobu, Mukai, Kuniaki, Turcu, Adina, Nishimoto, Koshiro, Yamaguchi, Kenya, Takahashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292187/
https://www.ncbi.nlm.nih.gov/pubmed/32743400
http://dx.doi.org/10.1002/iju5.12068
Descripción
Sumario:INTRODUCTION: Aberrant cortical adrenal tissues are not generally identified in adults. Herein, we present a very rare case of an ectopic adrenal tumor located in the renal hilum that caused gross hematuria. CASE PRESENTATION: A 33‐year‐old man suddenly presented with asymptomatic gross hematuria. Abdominal computed tomography revealed a 35‐mm mass in the left renal hilum encroaching the renal vein. Following the surgical removal with frozen section of the mass, his gross hematuria immediately improved. Pathological analysis of the specimen revealed the features adrenal adenoma. Immunohistochemical staining for key steroidogenic enzymes confirmed the adrenocortical origin without excessive hormone production. CONCLUSION: This is the first case of an ectopic adrenocortical adenoma in the renal hilum that caused gross hematuria without hormonal symptoms.

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