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OX(2) receptors mediate the inhibitory effects of orexin‐A on potassium chloride‐induced increases in intracellular calcium ion levels in neurons derived from rat dorsal root ganglion in a chronic pain model
AIMS: Orexin‐A is known to induce anti‐nociceptive effects in animal models of chronic pain. We have found that orexin‐A inhibits KCl loading‐induced increases in the intracellular calcium ion levels ([Ca(2+)](i)) in C‐fiber‐like neurons of rats showing inflammatory nociceptive behavior. Here, we ex...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292216/ https://www.ncbi.nlm.nih.gov/pubmed/31845549 http://dx.doi.org/10.1002/npr2.12094 |