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Influence of Body Mass Index ≥30 on Pure Laparoscopic Donor Right Hepatectomy

BACKGROUND: Pure laparoscopic donor right hepatectomy (PLDRH) for donors with obesity has not been previously investigated. This study aimed to investigate the influence of donor obesity (BMI ≥30 kg/m(2)) on and clinical outcomes after PLDRH. MATERIAL/METHODS: Records of all living donors who underw...

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Autores principales: Hong, Suk Kyun, Suh, Kyung-Suk, Cho, Jae-Hyung, Lee, Jeong-Moo, Yi, Nam-Joon, Lee, Kwang-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292238/
https://www.ncbi.nlm.nih.gov/pubmed/32483107
http://dx.doi.org/10.12659/AOT.923094
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author Hong, Suk Kyun
Suh, Kyung-Suk
Cho, Jae-Hyung
Lee, Jeong-Moo
Yi, Nam-Joon
Lee, Kwang-Woong
author_facet Hong, Suk Kyun
Suh, Kyung-Suk
Cho, Jae-Hyung
Lee, Jeong-Moo
Yi, Nam-Joon
Lee, Kwang-Woong
author_sort Hong, Suk Kyun
collection PubMed
description BACKGROUND: Pure laparoscopic donor right hepatectomy (PLDRH) for donors with obesity has not been previously investigated. This study aimed to investigate the influence of donor obesity (BMI ≥30 kg/m(2)) on and clinical outcomes after PLDRH. MATERIAL/METHODS: Records of all living donors who underwent PLDRH between November 2015 and May 2018 and open conventional donor right hepatectomy (CDRH) between January 2011 and October 2015 at Seoul National University Hospital were retrospectively reviewed. The donors were divided into 3 groups: PLDRH BMI ≥30, PLDRH BMI <30, and CDRH BMI ≥30. RESULTS: Donors in the PLDRH BMI ≥30 group (n=7) were compared with those in the PLDRH BMI <30 (n=65; control 1) and CDRH BMI ≥30 (n=8; control 2) groups. Graft weight was significantly heavier in PLDRH BMI ≥30 than in control 1 (P=0.012). The lowest hemoglobin (Hb) value was higher (P=0.014) and ΔHb% was lower (P=0.005) in PLDRH BMI ≥30 than in control 1. Similarly, the lowest Hb value was higher (P=0.021) and ΔHb% was lower (P<0.001) in PLDRH BMI ≥30 than in control 2. The peak alanine aminotransferase (ALT) (P=0.029) and ΔALT% were higher in PLDRH BMI ≥30 than in control 2. No significant differences in hospital stay and postoperative complications were found between PLDRH BMI ≥3 and control 1, as well as between PLDRH BMI ≥3 and control 2. CONCLUSIONS: This study revealed that PLDRH is feasible in donors with obesity.
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spelling pubmed-72922382020-06-19 Influence of Body Mass Index ≥30 on Pure Laparoscopic Donor Right Hepatectomy Hong, Suk Kyun Suh, Kyung-Suk Cho, Jae-Hyung Lee, Jeong-Moo Yi, Nam-Joon Lee, Kwang-Woong Ann Transplant Original Paper BACKGROUND: Pure laparoscopic donor right hepatectomy (PLDRH) for donors with obesity has not been previously investigated. This study aimed to investigate the influence of donor obesity (BMI ≥30 kg/m(2)) on and clinical outcomes after PLDRH. MATERIAL/METHODS: Records of all living donors who underwent PLDRH between November 2015 and May 2018 and open conventional donor right hepatectomy (CDRH) between January 2011 and October 2015 at Seoul National University Hospital were retrospectively reviewed. The donors were divided into 3 groups: PLDRH BMI ≥30, PLDRH BMI <30, and CDRH BMI ≥30. RESULTS: Donors in the PLDRH BMI ≥30 group (n=7) were compared with those in the PLDRH BMI <30 (n=65; control 1) and CDRH BMI ≥30 (n=8; control 2) groups. Graft weight was significantly heavier in PLDRH BMI ≥30 than in control 1 (P=0.012). The lowest hemoglobin (Hb) value was higher (P=0.014) and ΔHb% was lower (P=0.005) in PLDRH BMI ≥30 than in control 1. Similarly, the lowest Hb value was higher (P=0.021) and ΔHb% was lower (P<0.001) in PLDRH BMI ≥30 than in control 2. The peak alanine aminotransferase (ALT) (P=0.029) and ΔALT% were higher in PLDRH BMI ≥30 than in control 2. No significant differences in hospital stay and postoperative complications were found between PLDRH BMI ≥3 and control 1, as well as between PLDRH BMI ≥3 and control 2. CONCLUSIONS: This study revealed that PLDRH is feasible in donors with obesity. International Scientific Literature, Inc. 2020-06-02 /pmc/articles/PMC7292238/ /pubmed/32483107 http://dx.doi.org/10.12659/AOT.923094 Text en © Ann Transplant, 2020 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Original Paper
Hong, Suk Kyun
Suh, Kyung-Suk
Cho, Jae-Hyung
Lee, Jeong-Moo
Yi, Nam-Joon
Lee, Kwang-Woong
Influence of Body Mass Index ≥30 on Pure Laparoscopic Donor Right Hepatectomy
title Influence of Body Mass Index ≥30 on Pure Laparoscopic Donor Right Hepatectomy
title_full Influence of Body Mass Index ≥30 on Pure Laparoscopic Donor Right Hepatectomy
title_fullStr Influence of Body Mass Index ≥30 on Pure Laparoscopic Donor Right Hepatectomy
title_full_unstemmed Influence of Body Mass Index ≥30 on Pure Laparoscopic Donor Right Hepatectomy
title_short Influence of Body Mass Index ≥30 on Pure Laparoscopic Donor Right Hepatectomy
title_sort influence of body mass index ≥30 on pure laparoscopic donor right hepatectomy
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292238/
https://www.ncbi.nlm.nih.gov/pubmed/32483107
http://dx.doi.org/10.12659/AOT.923094
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