Cargando…

Safety and Efficacy of Centanafadine Sustained-Release in Adults With Attention-Deficit Hyperactivity Disorder: Results of Phase 2 Studies

PURPOSE: Two phase 2 studies evaluated the efficacy and tolerability of centanafadine sustained-release (SR) for adults with attention-deficit/hyperactivity disorder (ADHD). PATIENTS AND METHODS: In a phase 2a, flexible-dose, single-blind study, 41 male patients (aged 18‒55 years) with a diagnosis o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wigal, Sharon B, Wigal, Tim, Hobart, Mary, Madera, Jessica J, Baker, Ross A, Kohegyi, Eva, McKinney, Anthony, Wilens, Timothy E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Clinical Trial Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292254/ https://www.ncbi.nlm.nih.gov/pubmed/32606695 http://dx.doi.org/10.2147/NDT.S242084

Ejemplares similares

Efficacy, Safety, and Tolerability of Centanafadine Sustained-Release Tablets in Adults With Attention-Deficit/Hyperactivity Disorder: Results of 2 Phase 3, Randomized, Double-blind, Multicenter, Placebo-Controlled Trials
por: Adler, Lenard A., et al.
Publicado: (2022)

Review of Clinical Outcome Assessments in Pediatric Attention-Deficit/Hyperactivity Disorder
por: Markowitz, Jessica T, et al.
Publicado: (2020)

A Double-Blind, Placebo-Controlled, Phase II Study to Determine the Efficacy, Safety, Tolerability and Pharmacokinetics of a Controlled Release (CR) Formulation of Mazindol in Adults with DSM-5 Attention-Deficit/Hyperactivity Disorder (ADHD)
por: Wigal, Tim L., et al.
Publicado: (2018)

Population pharmacokinetics of methylphenidate hydrochloride extended-release multiple-layer beads in pediatric subjects with attention deficit hyperactivity disorder
por: Teuscher, Nathan S, et al.
Publicado: (2015)

Efficacy and Safety of Amphetamine Extended-Release Oral Suspension in Children with Attention-Deficit/Hyperactivity Disorder
por: Childress, Ann C., et al.
Publicado: (2018)

Efficacy and Safety of a Chewable Methylphenidate Extended-Release Tablet in Children with Attention-Deficit/Hyperactivity Disorder
por: Wigal, Sharon B., et al.
Publicado: (2017)

A 13-hour laboratory school study of lisdexamfetamine dimesylate in school-aged children with attention-deficit/hyperactivity disorder
por: Wigal, Sharon B, et al.
Publicado: (2009)

Efficacy and tolerability of lisdexamfetamine dimesylate in children with attention-deficit/hyperactivity disorder: sex and age effects and effect size across the day
por: Wigal, Sharon B, et al.
Publicado: (2010)

Effect of Aptensio XR (Methylphenidate HCl Extended-Release) Capsules on Sleep in Children with Attention-Deficit/Hyperactivity Disorder
por: Owens, Judith, et al.
Publicado: (2016)

Efficacy of Methylphenidate Hydrochloride Extended-Release Capsules (Aptensio XR™) in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Phase III, Randomized, Double-Blind Study
por: Wigal, Sharon B., et al.
Publicado: (2015)

Effects of an 8-week yoga program on sustained attention and discrimination function in children with attention deficit hyperactivity disorder
por: Chou, Chien-Chih, et al.
Publicado: (2017)

AOD Use and Attention Deficit/Hyperactivity Disorder
por: Wilens, Timothy E.
Publicado: (1998)

Effect of Atomoxetine Treatment on Reading and Phonological Skills in Children with Dyslexia or Attention-Deficit/Hyperactivity Disorder and Comorbid Dyslexia in a Randomized, Placebo-Controlled Trial
por: Shaywitz, Sally, et al.
Publicado: (2017)

Randomized, double-blind, placebo-controlled, crossover study of the efficacy and safety of lisdexamfetamine dimesylate in adults with attention-deficit/hyperactivity disorder: novel findings using a simulated adult workplace environment design
por: Wigal, Timothy, et al.
Publicado: (2010)

A Randomized, Double-Blind, Placebo-Controlled Study of HLD200, a Delayed-Release and Extended-Release Methylphenidate, in Children with Attention-Deficit/Hyperactivity Disorder: An Evaluation of Safety and Efficacy Throughout the Day and Across Settings
por: Childress, Ann C., et al.
Publicado: (2020)

Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults
por: Matuskey, David, et al.
Publicado: (2022)

Long-Term Stimulant Treatment Affects Brain Dopamine Transporter Level in Patients with Attention Deficit Hyperactive Disorder
por: Wang, Gene-Jack, et al.
Publicado: (2013)

Laboratory School Protocol Mini-Review: Use of Direct Observational and Objective Measures to Assess ADHD Treatment Response Across the Lifespan
por: Wigal, Sharon B.
Publicado: (2019)

Efficacy and Safety of HLD200, Delayed-Release and Extended-Release Methylphenidate, in Children with Attention-Deficit/Hyperactivity Disorder
por: Pliszka, Steven R., et al.
Publicado: (2017)

Effect of non-pharmacological treatment on the full recovery of social functioning in patients with attention deficit hyperactivity disorder
por: Lv, Ying-Bo, et al.
Publicado: (2023)

Extended-Release Viloxazine Compared with Atomoxetine for Attention Deficit Hyperactivity Disorder
por: Price, Maxwell Z., et al.
Publicado: (2023)

Attention Patterns in Children with Attention Deficit Disorder with or without Hyperactivity
por: Zalsman, Gil, et al.
Publicado: (2003)

Longitudinal maturation of resting state networks: Relevance to sustained attention and attention deficit/hyperactivity disorder
por: Thomson, Phoebe, et al.
Publicado: (2022)

Cocaine or Methamphetamine Use During Young Adulthood Following Stimulant Use for Attention-Deficit/Hyperactivity Disorder During Adolescence
por: McCabe, Sean Esteban, et al.
Publicado: (2023)

Attenuated Tonic and Enhanced Phasic Release of Dopamine in Attention Deficit Hyperactivity Disorder
por: Badgaiyan, Rajendra D., et al.
Publicado: (2015)

Management of attention-deficit hyperactivity disorder
por: Verma, Rohit, et al.
Publicado: (2011)

The history of attention deficit hyperactivity disorder
por: Lange, Klaus W., et al.
Publicado: (2010)

Stigma in attention deficit hyperactivity disorder
por: Mueller, Anna K., et al.
Publicado: (2012)

Attention Deficit Hyperactivity Disorder and Athletes
por: White, Russell D., et al.
Publicado: (2014)

Driving and attention deficit hyperactivity disorder
por: Fuermaier, Anselm B. M., et al.
Publicado: (2015)

Genetics of attention deficit hyperactivity disorder
por: Faraone, Stephen V., et al.
Publicado: (2018)

Neuroimaging in attention-deficit/hyperactivity disorder
por: Pereira-Sanchez, Victor, et al.
Publicado: (2021)

Attention-deficit/hyperactive disorder updates
por: Kessi, Miriam, et al.
Publicado: (2022)

The Association Between Attention-Deficit Hyperactivity Disorder, Injuries, and Methylphenidate
por: Shem-Tov, Sharon, et al.
Publicado: (2019)

Profile of guanfacine extended release and its potential in the treatment of attention-deficit hyperactivity disorder
por: Martinez-Raga, Jose, et al.
Publicado: (2015)

Evaluation of acute cardiovascular effects of immediate-release methylphenidate in children and adolescents with attention-deficit hyperactivity disorder
por: Lamberti, Marco, et al.
Publicado: (2015)

Attention deficit hyperactivity disorder (ADHD) & COVID-19: Attention deficit hyperactivity disorder: Consequences of the 1st wave
por: Insa, I., et al.
Publicado: (2021)

Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with Autism
por: Christakou, A, et al.
Publicado: (2013)

Psychometric properties of Persian version of the Sustained Auditory Attention Capacity Test in children with attention deficit-hyperactivity disorder
por: Soltanparast, Sanaz, et al.
Publicado: (2014)

Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with Autism
por: Christakou, A, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3h507btde39tm57j0tkmbl05tp