Cargando…
Early manifestation of depressive‐like behavior in transgenic mice that express dementia with Lewy body‐linked mutant β‐synuclein
AIM: We previously generated transgenic (Tg) mice that expressed P123H β‐synuclein (βS), a dementia with Lewy body‐linked mutant βS. Notably, these mice recapitulated neurodegenerative features of Lewy body disease, reflected by motor dysfunction, greater protein aggregation, and memory impairment....
Autores principales: | Fujita, Masayo, Hagino, Yoko, Takamatsu, Yukio, Shimizu, Yuka, Takamatsu, Yoshiki, Ikeda, Kazutaka, Hashimoto, Makoto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292266/ https://www.ncbi.nlm.nih.gov/pubmed/30106256 http://dx.doi.org/10.1002/npr2.12009 |
Ejemplares similares
-
Possible Role of Amyloidogenic Evolvability in Dementia with Lewy Bodies: Insights from Transgenic Mice Expressing P123H β-Synuclein
por: Fujita, Masayo, et al.
Publicado: (2020) -
Immature-like molecular expression patterns in the hippocampus of a mouse model of dementia with Lewy body-linked mutant β-synuclein
por: Hagihara, Hideo, et al.
Publicado: (2018) -
Increase in excitability of hippocampal neurons during novelty-induced hyperlocomotion in dopamine-deficient mice
por: Fujita, Masayo, et al.
Publicado: (2020) -
Involvement of muscarinic receptors in psychomotor hyperactivity in dopamine-deficient mice
por: Fujita, Masayo, et al.
Publicado: (2022) -
Reward‐enhancing effect of methylphenidate is abolished in dopamine transporter knockout mice: A model of attention‐deficit/hyperactivity disorder
por: Ide, Soichiro, et al.
Publicado: (2018)