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Comprehensive behavioral analysis of tryptophan 2,3‐dioxygenase (Tdo2) knockout mice

AIMS: Tryptophan 2,3‐dioxygenase (TDO2) is an initial rate‐limiting enzyme of the kynurenine (Kyn) pathway in tryptophan (Trp) metabolism. The Trp‐degrading enzymes, TDO2 and indoleamine 2,3‐dioxygenase, are activated by stress and/or inflammation. Dysregulation of Trp metabolism, which causes shift...

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Detalles Bibliográficos
Autores principales:	Hattori, Satoko, Takao, Keizo, Funakoshi, Hiroshi, Miyakawa, Tsuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292271/ https://www.ncbi.nlm.nih.gov/pubmed/30106261 http://dx.doi.org/10.1002/npr2.12006

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