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Concurrent, successful management of bipolar I disorder with comorbid alcohol dependence via aripiprazole long‐acting injection: A case report
Alcohol dependence is frequently comorbid with bipolar I disorder. Aripiprazole and its long‐acting injection have demonstrated efficacy in the treatment and prevention of bipolar I disorder and its attendant symptoms, especially manic episodes. However, whether aripiprazole can alleviate alcohol de...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292293/ https://www.ncbi.nlm.nih.gov/pubmed/31325244 http://dx.doi.org/10.1002/npr2.12072 |
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author | Kurata, Tsutomu Hashimoto, Tasuku Suzuki, Hitoshi |
author_facet | Kurata, Tsutomu Hashimoto, Tasuku Suzuki, Hitoshi |
author_sort | Kurata, Tsutomu |
collection | PubMed |
description | Alcohol dependence is frequently comorbid with bipolar I disorder. Aripiprazole and its long‐acting injection have demonstrated efficacy in the treatment and prevention of bipolar I disorder and its attendant symptoms, especially manic episodes. However, whether aripiprazole can alleviate alcohol dependence remains controversial. We report the case of a 47‐year‐old woman who had been diagnosed with bipolar I disorder and alcohol dependence, characterized by poor adherence to pharmacological treatment and our hospital's alcoholic treatment program. Consequently, she was repeatedly hospitalized several times per year due to manic episodes and heavy drinking. After treatment with aripiprazole long‐acting injection at a dosage of 400 mg/mo intramuscularly, she has been relapse‐free for over 2 years. Aripiprazole long‐acting injection might therefore be effective for treating patients with bipolar disorder and a comorbid diagnosis of alcohol dependence. |
format | Online Article Text |
id | pubmed-7292293 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72922932020-12-08 Concurrent, successful management of bipolar I disorder with comorbid alcohol dependence via aripiprazole long‐acting injection: A case report Kurata, Tsutomu Hashimoto, Tasuku Suzuki, Hitoshi Neuropsychopharmacol Rep Case Report Alcohol dependence is frequently comorbid with bipolar I disorder. Aripiprazole and its long‐acting injection have demonstrated efficacy in the treatment and prevention of bipolar I disorder and its attendant symptoms, especially manic episodes. However, whether aripiprazole can alleviate alcohol dependence remains controversial. We report the case of a 47‐year‐old woman who had been diagnosed with bipolar I disorder and alcohol dependence, characterized by poor adherence to pharmacological treatment and our hospital's alcoholic treatment program. Consequently, she was repeatedly hospitalized several times per year due to manic episodes and heavy drinking. After treatment with aripiprazole long‐acting injection at a dosage of 400 mg/mo intramuscularly, she has been relapse‐free for over 2 years. Aripiprazole long‐acting injection might therefore be effective for treating patients with bipolar disorder and a comorbid diagnosis of alcohol dependence. John Wiley and Sons Inc. 2019-07-20 /pmc/articles/PMC7292293/ /pubmed/31325244 http://dx.doi.org/10.1002/npr2.12072 Text en © 2019 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Society of NeuropsychoPharmacology. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Kurata, Tsutomu Hashimoto, Tasuku Suzuki, Hitoshi Concurrent, successful management of bipolar I disorder with comorbid alcohol dependence via aripiprazole long‐acting injection: A case report |
title | Concurrent, successful management of bipolar I disorder with comorbid alcohol dependence via aripiprazole long‐acting injection: A case report |
title_full | Concurrent, successful management of bipolar I disorder with comorbid alcohol dependence via aripiprazole long‐acting injection: A case report |
title_fullStr | Concurrent, successful management of bipolar I disorder with comorbid alcohol dependence via aripiprazole long‐acting injection: A case report |
title_full_unstemmed | Concurrent, successful management of bipolar I disorder with comorbid alcohol dependence via aripiprazole long‐acting injection: A case report |
title_short | Concurrent, successful management of bipolar I disorder with comorbid alcohol dependence via aripiprazole long‐acting injection: A case report |
title_sort | concurrent, successful management of bipolar i disorder with comorbid alcohol dependence via aripiprazole long‐acting injection: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292293/ https://www.ncbi.nlm.nih.gov/pubmed/31325244 http://dx.doi.org/10.1002/npr2.12072 |
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