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Diosgenin and GSK126 Produce Synergistic Effects on Epithelial–Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway

BACKGROUND: Diosgenin, a natural steroidal saponin isolated from Trigonella foenum-graecum, has been reported to exert anti-cancer effects. Inhibitors of enhancer of zeste homology 2 (EZH2) have been widely used in treatment of cancers. However, the effects of combined treatment with diosgenin and a...

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Detalles Bibliográficos
Autores principales:	Liu, Shanshan, Rong, Guihong, Li, Xia, Geng, Lijun, Zeng, Zhineng, Jiang, Dongxiang, Yang, Jun, Wei, Yesheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292386/ https://www.ncbi.nlm.nih.gov/pubmed/32606728 http://dx.doi.org/10.2147/OTT.S237474

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