P55PIK Regulates P53-Dependent Apoptosis in Cancer Cells by Interacting with P53 DNA-Specific Domain

PURPOSE: Phosphatidylinositol 3-kinase (PI3K) plays an important role in tumorigenesis by cross-talking with several signaling pathways. p55PIK is a unique regulatory subunit of PI3K and contains an extra 24-residue N-terminal domain (N24). This study aimed to explore the interaction of p55PIK with...

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Detalles Bibliográficos
Autores principales: Li, Chaoxing, Li, Wenwen, Cheng, Xiyao, Zhang, Dapeng, Sun, Xiang, Zhou, Jingjing, Zhou, Yin, Huang, Yongqi, Xia, Xianmin, Ma, Qi, Su, Zhengding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292491/
https://www.ncbi.nlm.nih.gov/pubmed/32606738
http://dx.doi.org/10.2147/OTT.S247200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292491/
https://www.ncbi.nlm.nih.gov/pubmed/32606738
http://dx.doi.org/10.2147/OTT.S247200

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