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P55PIK Regulates P53-Dependent Apoptosis in Cancer Cells by Interacting with P53 DNA-Specific Domain
PURPOSE: Phosphatidylinositol 3-kinase (PI3K) plays an important role in tumorigenesis by cross-talking with several signaling pathways. p55PIK is a unique regulatory subunit of PI3K and contains an extra 24-residue N-terminal domain (N24). This study aimed to explore the interaction of p55PIK with...
Autores principales: | Li, Chaoxing, Li, Wenwen, Cheng, Xiyao, Zhang, Dapeng, Sun, Xiang, Zhou, Jingjing, Zhou, Yin, Huang, Yongqi, Xia, Xianmin, Ma, Qi, Su, Zhengding |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292491/ https://www.ncbi.nlm.nih.gov/pubmed/32606738 http://dx.doi.org/10.2147/OTT.S247200 |
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