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The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology

Quantitative systems pharmacology (QSP) has emerged as a transformative science in drug discovery and development. It is now time to fully rethink the biological functions of drug metabolizing enzymes (DMEs) and transporters within the framework of QSP models. The large set of DME and transporter ge...

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Detalles Bibliográficos
Autores principales:	Nigam, Sanjay K., Bush, Kevin T., Bhatnagar, Vibha, Poloyac, Samuel M., Momper, Jeremiah D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292762/ https://www.ncbi.nlm.nih.gov/pubmed/32119114 http://dx.doi.org/10.1002/cpt.1818

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