Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug–Drug Interaction Studies

Understanding transporter-mediated drug–drug interactions (DDIs) for investigational agents is important during drug development to assess DDI liability, its clinical relevance, and to determine appropriate DDI management strategies. P-glycoprotein (P-gp) is an efflux transporter that influences the...

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Detalles Bibliográficos
Autores principales: Elmeliegy, Mohamed, Vourvahis, Manoli, Guo, Cen, Wang, Diane D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292822/
https://www.ncbi.nlm.nih.gov/pubmed/32052379
http://dx.doi.org/10.1007/s40262-020-00867-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292822/
https://www.ncbi.nlm.nih.gov/pubmed/32052379
http://dx.doi.org/10.1007/s40262-020-00867-1

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