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Mechanical unfolding of a knotted protein unveils the kinetic and thermodynamic consequences of threading a polypeptide chain
Knots are remarkable topological features in nature. The presence of knots in crystallographic structures of proteins have stimulated considerable research to determine the kinetic and thermodynamic consequences of threading a polypeptide chain. By mechanically manipulating MJ0366, a small single do...
Autores principales: | Rivera, Maira, Hao, Yuxin, Maillard, Rodrigo A., Baez, Mauricio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292828/ https://www.ncbi.nlm.nih.gov/pubmed/32533020 http://dx.doi.org/10.1038/s41598-020-66258-5 |
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