Elastin homeostasis is altered with pelvic organ prolapse in cultures of vaginal cells from a lysyl oxidase‐like 1 knockout mouse model

Pelvic organ prolapse (POP) decreases quality of life for many women, but its pathophysiology is poorly understood. We have previously shown that Lysyl oxidase‐like 1 knockout (Loxl1 KO) mice reliably prolapse with age and increased parity, similar to women. Both this model and clinical studies also...

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Detalles Bibliográficos
Autores principales: Jameson, Slater A., Swaminathan, Ganesh, Dahal, Shataakshi, Couri, Bruna, Kuang, Mei, Rietsch, Anna, Butler, Robert S., Ramamurthi, Anand, Damaser, Margot S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292929/
https://www.ncbi.nlm.nih.gov/pubmed/32533648
http://dx.doi.org/10.14814/phy2.14436

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