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Prp5−Spt8/Spt3 interaction mediates a reciprocal coupling between splicing and transcription

Transcription and pre-mRNA splicing are coupled to promote gene expression and regulation. However, mechanisms by which transcription and splicing influence each other are still under investigation. The ATPase Prp5p is required for pre-spliceosome assembly and splicing proofreading at the branch-poi...

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Detalles Bibliográficos
Autores principales: Shao, Wei, Ding, Zhan, Zheng, Zeng-Zhang, Shen, Ji-Jia, Shen, Yu-Xian, Pu, Jia, Fan, Yu-Jie, Query, Charles C, Xu, Yong-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293005/
https://www.ncbi.nlm.nih.gov/pubmed/32399566
http://dx.doi.org/10.1093/nar/gkaa311