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Prp5−Spt8/Spt3 interaction mediates a reciprocal coupling between splicing and transcription
Transcription and pre-mRNA splicing are coupled to promote gene expression and regulation. However, mechanisms by which transcription and splicing influence each other are still under investigation. The ATPase Prp5p is required for pre-spliceosome assembly and splicing proofreading at the branch-poi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293005/ https://www.ncbi.nlm.nih.gov/pubmed/32399566 http://dx.doi.org/10.1093/nar/gkaa311 |