Structural disruption of exonic stem–loops immediately upstream of the intron regulates mammalian splicing

Recognition of highly degenerate mammalian splice sites by the core spliceosomal machinery is regulated by several protein factors that predominantly bind exonic splicing motifs. These are postulated to be single-stranded in order to be functional, yet knowledge of secondary structural features that...

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Detalles Bibliográficos
Autores principales: Saha, Kaushik, England, Whitney, Fernandez, Mike Minh, Biswas, Tapan, Spitale, Robert C, Ghosh, Gourisankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293017/
https://www.ncbi.nlm.nih.gov/pubmed/32402057
http://dx.doi.org/10.1093/nar/gkaa358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293017/
https://www.ncbi.nlm.nih.gov/pubmed/32402057
http://dx.doi.org/10.1093/nar/gkaa358

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