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Structural disruption of exonic stem–loops immediately upstream of the intron regulates mammalian splicing
Recognition of highly degenerate mammalian splice sites by the core spliceosomal machinery is regulated by several protein factors that predominantly bind exonic splicing motifs. These are postulated to be single-stranded in order to be functional, yet knowledge of secondary structural features that...
Autores principales: | Saha, Kaushik, England, Whitney, Fernandez, Mike Minh, Biswas, Tapan, Spitale, Robert C, Ghosh, Gourisankar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293017/ https://www.ncbi.nlm.nih.gov/pubmed/32402057 http://dx.doi.org/10.1093/nar/gkaa358 |
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