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Pby1 is a direct partner of the Dcp2 decapping enzyme

Most eukaryotic mRNAs harbor a characteristic 5′ m(7)GpppN cap that promotes pre-mRNA splicing, mRNA nucleocytoplasmic transport and translation while also protecting mRNAs from exonucleolytic attacks. mRNA caps are eliminated by Dcp2 during mRNA decay, allowing 5′-3′ exonucleases to degrade mRNA bo...

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Detalles Bibliográficos
Autores principales:	Charenton, Clément, Gaudon-Plesse, Claudine, Back, Régis, Ulryck, Nathalie, Cosson, Loreline, Séraphin, Bertrand, Graille, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293026/ https://www.ncbi.nlm.nih.gov/pubmed/32396195 http://dx.doi.org/10.1093/nar/gkaa337

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