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Adenovector 26 encoded prefusion conformation stabilized RSV-F protein induces long-lasting Th1-biased immunity in neonatal mice
While RSV is a major cause of respiratory morbidity in infants, vaccine development is hindered by the immaturity and Th2-bias of the infant immune system and the legacy of enhanced respiratory disease (ERD) after RSV infection following immunization with formalin inactivated (FI)-RSV vaccine in ear...
Autores principales: | van der Fits, Leslie, Bolder, Renske, Heemskerk-van der Meer, Marjolein, Drijver, Joke, van Polanen, Yolinda, Serroyen, Jan, Langedijk, Johannes P. M., Schuitemaker, Hanneke, Saeland, Eirikur, Zahn, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293210/ https://www.ncbi.nlm.nih.gov/pubmed/32566260 http://dx.doi.org/10.1038/s41541-020-0200-y |
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