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TECPR1 promotes aggrephagy by direct recruitment of LC3C autophagosomes to lysosomes
The accumulation of protein aggregates is involved in the onset of many neurodegenerative diseases. Aggrephagy is a selective type of autophagy that counteracts neurodegeneration by degrading such aggregates. In this study, we found that LC3C cooperates with lysosomal TECPR1 to promote the degradati...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293217/ https://www.ncbi.nlm.nih.gov/pubmed/32532970 http://dx.doi.org/10.1038/s41467-020-16689-5 |