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GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells

Glial-cell-derived neurotrophic factor (GDNF) is a well-studied neuroregenerative factor; however, the degree to which it supports hair formation and skin wound repair is not known. By using a Gfra1 (GDNF family receptor alpha 1) knock-in reporter mouse line, GDNF signaling was found to occur within...

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Detalles Bibliográficos
Autores principales: Lisse, Thomas S., Sharma, Manju, Vishlaghi, Neda, Pullagura, Sri Ramulu, Braun, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293257/
https://www.ncbi.nlm.nih.gov/pubmed/32566252
http://dx.doi.org/10.1038/s41536-020-0098-z