Prevalence of disease-causing genes in Japanese patients with BRCA1/2-wildtype hereditary breast and ovarian cancer syndrome

Panel sequencing of susceptibility genes for hereditary breast and ovarian cancer (HBOC) syndrome has uncovered numerous germline variants; however, their pathogenic relevance and ethnic diversity remain unclear. Here, we examined the prevalence of germline variants among 568 Japanese patients with...

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Detalles Bibliográficos
Autores principales: Kaneyasu, Tomoko, Mori, Seiichi, Yamauchi, Hideko, Ohsumi, Shozo, Ohno, Shinji, Aoki, Daisuke, Baba, Shinichi, Kawano, Junko, Miki, Yoshio, Matsumoto, Naomichi, Nagasaki, Masao, Yoshida, Reiko, Akashi-Tanaka, Sadako, Iwase, Takuji, Kitagawa, Dai, Masuda, Kenta, Hirasawa, Akira, Arai, Masami, Takei, Junko, Ide, Yoshimi, Gotoh, Osamu, Yaguchi, Noriko, Nishi, Mitsuyo, Kaneko, Keika, Matsuyama, Yumi, Okawa, Megumi, Suzuki, Misato, Nezu, Aya, Yokoyama, Shiro, Amino, Sayuri, Inuzuka, Mayuko, Noda, Tetsuo, Nakamura, Seigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293299/
https://www.ncbi.nlm.nih.gov/pubmed/32566746
http://dx.doi.org/10.1038/s41523-020-0163-1

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