Intracellular virus sensor MDA5 exacerbates vitiligo by inducing the secretion of chemokines in keratinocytes under virus invasion

Vitiligo is a disfiguring disease featuring chemokines-mediated cutaneous infiltration of autoreactive CD8(+) T cells that kill melanocytes. Copious studies have indicated that virus invasion participates in the pathogenesis of vitiligo. IFIH1, encoding MDA5 which is an intracellular virus sensor, h...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuang, Tongtian, Yi, Xiuli, Chen, Jianru, Kang, Pan, Chen, Xuguang, Chen, Jiaxi, Cui, Tingting, Chang, Yuqian, Ye, Zhubiao, Ni, Qingrong, Wang, Yinghan, Du, Pengran, Li, Baizhang, Liu, Ling, Jian, Zhe, Li, Kai, Gao, Tianwen, Li, Shuli, Li, Chunying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293308/
https://www.ncbi.nlm.nih.gov/pubmed/32532953
http://dx.doi.org/10.1038/s41419-020-2665-z

Ejemplares similares

Ejemplares similares