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Metabolic reprogramming related to whole-chromosome instability in models for Hürthle cell carcinoma

Hürthle cell carcinoma (HCC) is a recurrent subtype of non-medullary thyroid cancer. HCC is characterized by profound whole-chromosome instability (w-CIN), resulting in a near-homozygous genome (NHG), a phenomenon recently attributed to reactive oxygen species (ROS) generated during mitosis by malfu...

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Detalles Bibliográficos
Autores principales:	Addie, Ruben D., Kostidis, Sarantos, Corver, Willem E., Oosting, Jan, Aminzadeh-Gohari, Sepideh, Feichtinger, René G., Kofler, Barbara, Aydemirli, Mehtap Derya, Giera, Martin, Morreau, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293353/ https://www.ncbi.nlm.nih.gov/pubmed/32533088 http://dx.doi.org/10.1038/s41598-020-66599-1

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